Henry Lynch
亨利·林奇
MD, PhD
Distinguished McKie Chair in Clinical Genetics (Emeritus)临床遗传学麦基杰出讲席教授（荣休）
👥Biography 个人简介
Legendary oncologist who first described hereditary non-polyposis colorectal cancer (HNPCC), now called Lynch syndrome, in the 1960s. His five decades of research on cancer family syndromes established hereditary cancer as a distinct clinical entity requiring specialized surveillance.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Lynch Syndrome Discovery
Identified and characterized Lynch syndrome through meticulous family studies over decades, demonstrating autosomal dominant inheritance of colorectal and endometrial cancer susceptibility.
Hereditary Cancer Registries
Established one of the world's largest hereditary cancer family registries at Creighton, enabling landmark genetic epidemiology studies on familial cancer syndromes.
Representative Works 代表性著作
Hereditary factors in cancer: study of two large midwestern kindreds
Archives of Internal Medicine (1966)
First description of Lynch syndrome families establishing hereditary non-polyposis colorectal cancer as a distinct hereditary syndrome.
Hereditary colorectal cancer
New England Journal of Medicine (2003)
Comprehensive review of Lynch syndrome genetics, clinical features, and surveillance recommendations.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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University of Washington
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Barbara Biesecker
RTI International / NHGRI
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