Gareth Evans

Gareth Evans, MD, FRCP, FMedSci is Professor and Chair of Medical Genetics at the University of Manchester and a Consultant in Medical Genetics and Cancer Epidemiology at Manchester University NHS Foundation Trust. He is Co-Director of the Genesis Breast Cancer Prevention Centre — one of Europe's foremost centers for familial breast cancer research and prevention. Over a 35-year career, Professor Evans has become one of the world's leading authorities on the clinical management of hereditary breast and ovarian cancer, with particular expertise in BRCA1 and BRCA2 mutation carriers, risk-reducing surgery, chemoprevention, and the development of validated risk prediction models. He developed the Manchester Scoring System, a widely used clinical tool for estimating the probability of a BRCA mutation based on family history, which has been incorporated into national screening guidelines across multiple countries. Professor Evans has led large prospective studies following thousands of BRCA mutation carriers and high-risk women, generating definitive data on the efficacy of risk-reducing mastectomy and salpingo-oophorectomy in preventing cancer and cancer death. He has also been a leading investigator in breast cancer chemoprevention trials for high-risk populations, contributing to IBIS-I (tamoxifen), IBIS-II (anastrozole), and multiple UK national prevention cohorts. He has authored over 600 peer-reviewed publications and is a Fellow of the Academy of Medical Sciences.