Felix Hilpert
菲利克斯·希尔珀特
MD, PhD
Director, Gynecological Oncology妇科肿瘤学主任
👥Biography 个人简介
Felix Hilpert is Director of Gynecological Oncology at Krankenhaus Jerusalem Hamburg and an internationally recognized surgical oncologist specializing in advanced ovarian cancer. He was the principal investigator of the landmark LION trial (Lymphadenectomy in Ovarian Neoplasms), which definitively demonstrated that systematic pelvic and para-aortic lymphadenectomy does not improve survival in women with advanced ovarian cancer achieving complete macroscopic resection, published in NEJM 2019.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
LION Trial: Lymphadenectomy in Advanced Ovarian Cancer
PI of the LION phase III RCT, demonstrating that systematic lymphadenectomy did not improve overall or progression-free survival vs no lymphadenectomy in advanced ovarian cancer with complete cytoreduction, fundamentally changing surgical practice guidelines worldwide.
Cytoreductive Surgery Quality Standards in Ovarian Cancer
Contributed to AGO-OVAR surgical quality initiatives, defining standards for complete cytoreduction and metrics for surgical excellence in advanced ovarian cancer, and investigating the prognostic impact of residual disease status after primary surgery.
Representative Works 代表性著作
Lymphadenectomy in Patients with Advanced Ovarian Neoplasms (LION)
New England Journal of Medicine (2019)
Phase III RCT demonstrating systematic lymphadenectomy did not improve survival outcomes in optimally debulked advanced ovarian cancer, removing routine lymphadenectomy from surgical standards.
Prognostic Value of Residual Disease Status After Primary Cytoreductive Surgery in Advanced Ovarian Cancer
Annals of Surgical Oncology (2021)
Confirmed complete macroscopic cytoreduction as the critical surgical endpoint associated with prolonged survival in advanced ovarian cancer across AGO-OVAR cohorts.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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