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clinical / clinicalEuropean HER2+ breast cancer trials

Evandro de Azambuja

埃万德罗·德·阿赞布贾

MD, PhD

🏢Institut Jules Bordet, Universite Libre de Bruxelles(朱尔博尔代研究所)🌐Belgium

Head of Research研究主任

65
h-index
2
Key Papers
1
Awards
2
Key Contributions

👥Biography 个人简介

Evandro de Azambuja at Institut Jules Bordet is a leading European breast cancer trialist and one of the principal investigators of the APHINITY trial demonstrating pertuzumab adjuvant benefit. He leads the Breast International Group (BIG) statistical center.

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🧪Research Fields 研究领域

HER2-positive breast cancerHER2阳性乳腺癌
pertuzumab帕妥珠单抗
neoadjuvant therapy新辅助治疗
APHINITY trialAPHINITY试验
European breast cancer欧洲乳腺癌

🎓Key Contributions 主要贡献

APHINITY Trial

Was among the principal investigators of APHINITY, demonstrating that adjuvant pertuzumab plus trastuzumab reduces invasive disease events in HER2+ early breast cancer.

BIG Statistical Leadership

Leads statistical operations and data management for Breast International Group cooperative trials, enabling global HER2+ breast cancer research.

Representative Works 代表性著作

[1]

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer

NEJM (2017)

APHINITY trial.

[2]

Pertuzumab, Trastuzumab, and Standard Adjuvant Chemotherapy for Women with Early, HER2-Positive Breast Cancer: Updated results of APHINITY

Journal of Clinical Oncology (2021)

6-year APHINITY follow-up.

🏆Awards & Recognition 奖项与荣誉

🏆ESMO Award for Excellence in Breast Cancer Research

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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