Ethan Basch
伊森·巴什
MD, MSc
Professor of Medicine; Director, Cancer Outcomes Research Program; Lineberger Comprehensive Cancer Center医学教授；癌症结局研究项目主任；Lineberger综合癌症中心
👥Biography 个人简介
Ethan Basch is a world leader in patient-reported outcomes (PRO) research in oncology. His landmark randomized trials demonstrated that electronic symptom monitoring with PROs improves survival, reduces hospitalizations, and enhances quality of life in cancer patients. He chairs ASCO's PRO working group and has driven international PRO standards.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Electronic PRO Survival Benefit
Conducted the pivotal RCT showing that web-based electronic symptom monitoring during chemotherapy improved overall survival by 5 months versus standard care — the first trial to link PROs to a survival benefit.
ASCO PRO Implementation Guidelines
Led development of ASCO's clinical practice guidelines for routine PRO collection in oncology, providing a framework adopted internationally to standardize patient-centered quality measurement.
PRO Measure Development
Developed and validated multiple PRO instruments used in FDA submissions and major clinical trials, advancing regulatory acceptance of patient-reported endpoints as primary efficacy measures.
Representative Works 代表性著作
Symptom Monitoring with Patient-Reported Outcomes During Routine Cancer Treatment
Journal of Clinical Oncology (2017)
Randomized trial of 766 patients showing web-based symptom monitoring improved overall survival and reduced ED visits compared to standard care.
Overall Survival Results of a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring
JAMA (2017)
Long-term OS data from landmark PRO monitoring RCT demonstrating a 5-month survival improvement with electronic symptom reporting.
Patient-Reported Outcomes as a Regulatory Endpoint in Clinical Trials
Journal of Clinical Oncology (2020)
Comprehensive review of FDA guidance and strategies for incorporating PRO endpoints as primary or key secondary efficacy measures in oncology trials.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Hope S. Rugo
University of California, San Francisco (UCSF)
Maryam B. Lustberg
Yale School of Medicine / Yale Cancer Center
Sara M. Tolaney
Dana-Farber Cancer Institute / Harvard Medical School
Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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