Eric J. Sherman
埃里克·谢尔曼
MD
Associate Attending Physician副主诊医师
👥Biography 个人简介
Eric Sherman is a thyroid cancer medical oncologist at Memorial Sloan Kettering who has contributed to development of multiple targeted therapies for advanced thyroid cancer. He led or co-led trials of cabozantinib in medullary thyroid cancer, lenvatinib in differentiated thyroid cancer, and has been central to investigation of RET inhibitors selpercatinib and pralsetinib in RET-mutant MTC. Sherman has contributed to understanding of BRAF V600E-positive anaplastic thyroid cancer and the impressive activity of BRAF/MEK inhibitor combinations in this otherwise rapidly fatal disease. He serves on ATA guideline committees for advanced thyroid cancer management.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
RET Inhibitors in Medullary Thyroid Cancer
Contributed to clinical development of selpercatinib and pralsetinib as potent RET inhibitors in RET-mutant medullary thyroid cancer, demonstrating high response rates and contributing to regulatory approvals.
Anaplastic Thyroid Cancer BRAF Targeting
Contributed to evidence establishing BRAF/MEK inhibitor combinations (dabrafenib/trametinib) in BRAF V600E anaplastic thyroid cancer, one of the most dramatic responses to targeted therapy in oncology.
Representative Works 代表性著作
Cabozantinib in Progressive Medullary Thyroid Cancer
Journal of Clinical Oncology (2013)
Phase III cabozantinib trial in medullary thyroid cancer.
Selpercatinib in RET-Mutant Medullary Thyroid Carcinoma
New England Journal of Medicine (2020)
LIBRETTO-001 establishing selpercatinib in RET-mutant thyroid cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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