Elizabeth M. Jaffee

Elizabeth Jaffee is a leader in cancer vaccine development with particular focus on pancreatic cancer. Her laboratory has developed GVAX, a granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting tumor cell vaccine, and combination strategies to overcome immunosuppression in pancreatic cancer. Jaffee's work has advanced understanding of how to convert immunologically "cold" tumors to "hot" tumors.

Elizabeth Jaffee是癌症疫苗开发的领导者，特别关注胰腺癌。她的实验室开发了GVAX，一种分泌粒细胞-巨噬细胞集落刺激因子（GM-CSF）的肿瘤细胞疫苗，以及克服胰腺癌免疫抑制的组合策略。Jaffee的工作推进了如何将免疫学"冷"肿瘤转化为"热"肿瘤的理解。