Domenica Lorusso
多梅尼卡·洛鲁索
MD, PhD
Senior Medical Oncologist, Division of Medical Gynecologic Oncology妇科肿瘤内科高级医师
👥Biography 个人简介
Domenica Lorusso, MD, PhD is a senior gynecologic oncologist at Italy's Istituto Nazionale dei Tumori and a principal investigator in major European (ENGOT) endometrial cancer trials, leading research on immunotherapy and molecular classification to personalize treatment.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
ENGOT Endometrial Cancer Clinical Trials Leadership
Served as PI and coordinating investigator in multiple ENGOT endometrial cancer trials, contributing to establishment of immunotherapy and targeted therapy standards across Europe.
Molecular Classification-Guided Treatment in Endometrial Cancer
Advanced integration of ProMisE/TCGA molecular classification into European clinical practice, demonstrating improved patient stratification and outcomes-based treatment selection.
Representative Works 代表性著作
Carboplatin-paclitaxel alone or with dostarlimab followed by maintenance dostarlimab in recurrent/advanced endometrial cancer (ENGOT-EN6/GOG-3031/RUBY)
New England Journal of Medicine (2023)
Co-investigator on the RUBY trial demonstrating survival benefit of dostarlimab plus chemotherapy in dMMR/MSI-H advanced endometrial cancer.
Molecular subtype and response to chemotherapy in endometrial cancer: an ENGOT study
Annals of Oncology (2021)
Demonstrated molecular subtype predicts chemotherapy benefit in endometrial cancer, advocating for routine molecular profiling in European clinical practice.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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