David Miklos
大卫·米克洛斯
MD, PhD
Associate Professor of Medicine, Director of Cellular Therapy医学副教授,细胞治疗主任
👥Biography 个人简介
David Miklos is a leading expert at Stanford combining allogeneic stem cell transplantation with cutting-edge CAR-T cell therapies, pioneering integration of cellular immunotherapy approaches for CLL, lymphoma, and post-transplant relapse management.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CAR-T and Transplant Integration
Led Stanford's efforts integrating CAR-T cell therapy with allogeneic SCT, developing sequential treatment strategies that leverage both modalities to eliminate minimal residual disease and prevent relapse.
CLL Transplant Outcomes
Conducted landmark analyses of allogeneic SCT outcomes in CLL, defining patient selection criteria and demonstrating long-term cure potential even in high-risk relapsed/refractory disease.
Representative Works 代表性著作
Axicabtagene ciloleucel CAR T-cell therapy in relapsed or refractory large B-cell lymphoma
New England Journal of Medicine (2017)
ZUMA-1 trial demonstrating durable remissions with axi-cel, establishing CAR-T as curative option for r/r LBCL.
Allogeneic stem cell transplantation provides durable remission in patients with chronic lymphocytic leukemia
Biology of Blood and Marrow Transplantation (2021)
Long-term follow-up study confirming curative potential of allo-SCT in high-risk CLL with 10+ year survivors.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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