Cora N. Sternberg
科拉·斯滕贝格
MD, FACP
Professor of Medicine; Clinical Director, Englander Institute for Precision Medicine医学教授暨恩格兰德精准医学研究所临床主任
👥Biography 个人简介
Pioneering urothelial cancer specialist with four decades of leadership, Prof. Sternberg developed MVAC chemotherapy regimens, contributed to EV-301 establishing enfortumab vedotin post-platinum standard, and has driven international guidelines through EAU and ASCO committee leadership.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
MVAC Chemotherapy Development
Co-developed the MVAC (methotrexate, vinblastine, doxorubicin, cisplatin) regimen that became the gold standard for metastatic bladder cancer for two decades, and led dose-dense MVAC trials that improved tolerability and efficacy.
EV-301 and ADC Standards
Key contributor to the EV-301 phase III trial demonstrating enfortumab vedotin improved OS versus chemotherapy in platinum- and checkpoint inhibitor-pretreated urothelial carcinoma, establishing ADC therapy as the second-line standard.
Representative Works 代表性著作
Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma (EV-301)
New England Journal of Medicine (2021)
Phase III trial establishing enfortumab vedotin as standard of care for post-platinum, post-checkpoint inhibitor metastatic urothelial carcinoma.
Methotrexate, Vinblastine, Doxorubicin, and Cisplatin for Advanced Transitional Cell Carcinoma of the Urothelium
Journal of Clinical Oncology (1988)
Landmark trial establishing MVAC as the first effective systemic regimen for metastatic bladder cancer, a cornerstone of treatment for decades.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Carlos H. Barrios
PUCRS (Pontifical Catholic University of Rio Grande do Sul) / Hospital São Lucas, Porto Alegre, Brazil
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