Carien L. Creutzberg

Carien L. Creutzberg, MD, PhD is Professor of Radiation Oncology at Leiden University Medical Center and an internationally recognized leader in the management of endometrial cancer. She leads the PORTEC (Post Operative Radiation Therapy in Endometrial Cancer) trial series, whose four landmark randomized trials have defined the global standard of care for adjuvant therapy in endometrial cancer and established the use of molecular subtype classification to guide treatment decisions. Her work integrating TCGA-based molecular classifications—including mismatch repair deficiency, POLE ultramutated, p53-abnormal, and no-specific-molecular-profile subtypes—has transformed how endometrial cancer is staged and treated worldwide.