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clinical / clinicalradiation biology

Ben J. Slotman

本·斯洛特曼

MD, PhD

🏢Amsterdam University Medical Centers (VUmc)(阿姆斯特丹大学医学中心)🌐Netherlands

Professor and Chair, Department of Radiation Oncology放射肿瘤学系教授兼系主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Ben Slotman is a pioneering radiation oncologist and a leader in MR-Linac adaptive radiotherapy who played a key role in establishing the MRIdian and Unity MR-Linac systems for clinical use. He has led major international trials in lung cancer SBRT, prophylactic cranial irradiation, and adaptive MRI-guided radiotherapy, and was instrumental in founding the MR-Linac Consortium—a global collaboration that has accelerated clinical adoption and evidence generation for this transformative technology.

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🧪Research Fields 研究领域

MR-Linac Adaptive RadiotherapyMR-Linac自适应放疗
Online Adaptive Radiation Therapy在线自适应放疗
MRI-Guided Radiation TherapyMRI引导放疗
Oligometastatic Disease寡转移性疾病
SBRT for Lung Cancer肺癌SBRT
Brain Metastases Radiotherapy脑转移放疗

🎓Key Contributions 主要贡献

MR-Linac Consortium Leadership

Co-founded and led the international MR-Linac Consortium, bringing together 14 institutions across Europe, North America, and Australia to collaboratively develop clinical protocols and generate evidence for MRI-guided adaptive radiotherapy.

Prophylactic Cranial Irradiation in SCLC

Led the landmark EORTC phase III trial (2007) demonstrating that prophylactic cranial irradiation significantly reduces brain metastases and improves overall survival in extensive-disease small cell lung cancer patients, changing standard of care globally.

Online Adaptive Radiotherapy Workflows

Developed and validated online adapt-to-shape and adapt-to-position workflows on the Elekta Unity MR-Linac, enabling same-day replanning based on daily MRI-visible anatomy changes for prostate, cervix, and abdominal tumors.

Representative Works 代表性著作

[1]

Prophylactic cranial irradiation in extensive small-cell lung cancer

New England Journal of Medicine (2007)

Practice-changing EORTC phase III trial demonstrating survival benefit of prophylactic cranial irradiation in extensive-stage SCLC.

[2]

MR-guided adaptive radiotherapy for primary tumors and oligometastatic disease

Seminars in Radiation Oncology (2019)

Comprehensive overview of MR-Linac clinical implementation, adaptive workflow, and early outcomes from the Consortium.

[3]

First-in-human online daily adaptive radiotherapy of the prostate on a 1.5T MR-Linac

International Journal of Radiation Oncology Biology Physics (2019)

Report of the first clinical treatments on the Elekta Unity MR-Linac, demonstrating feasibility of online adaptive radiotherapy.

🏆Awards & Recognition 奖项与荣誉

🏆ASTRO Elected Honorary Member
🏆ESTRO Honorary Member
🏆Dutch Cancer Society Research Award
🏆Netherlands Royal Society of Sciences and Humanities Fellowship

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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