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neuro-oncology / neuro-oncologyCNS Lymphoma

Antonio Omuro

安东尼奥·奥穆罗

MD

🏢Yale School of Medicine / Yale Cancer Center(耶鲁医学院 / 耶鲁癌症中心)🌐USA

Professor of Neurology; Director, Brain Tumor Program脑肿瘤项目主任、神经内科教授

48
h-index
2
Key Papers
3
Awards
3
Key Contributions

👥Biography 个人简介

Antonio Omuro directs Yale's Brain Tumor Program and is a leading authority on CNS lymphoma and GBM. He has designed and led pivotal trials for primary CNS lymphoma treatment and serves as a principal investigator in international neuro-oncology consortia.

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🧪Research Fields 研究领域

Neuro-oncology神经肿瘤学
Brain Tumors脑肿瘤
CNS Lymphoma中枢神经系统淋巴瘤
GBM胶质母细胞瘤

🎓Key Contributions 主要贡献

CNS Lymphoma

Led IELSG and CALGB trials that established methotrexate-based regimens with rituximab as standard care for primary CNS lymphoma.

GBM Trials

Served as principal investigator on multiple phase I/II GBM trials evaluating checkpoint inhibitors, vaccines, and targeted agents.

Leptomeningeal Disease

Contributed clinical research on intra-CSF therapies and systemic approaches for leptomeningeal metastases from solid tumors.

Representative Works 代表性著作

[1]

Rituximab and methotrexate with or without consolidation autologous stem cell transplantation in newly diagnosed primary CNS lymphoma

JAMA Oncology (2015)

Established efficacy of rituximab-methotrexate induction for CNS lymphoma with SCT consolidation in eligible patients.

[2]

Nivolumab with or without ipilimumab in patients with recurrent glioblastoma

Neuro-Oncology (2020)

CheckMate 143 expansion cohort demonstrating safety and limited efficacy of dual checkpoint blockade in recurrent GBM.

🏆Awards & Recognition 奖项与荣誉

🏆American Brain Tumor Association Research Award
🏆SNO Young Investigator Award
🏆French National Cancer Institute Prize

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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