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clinical / clinicalovarian cancer PARP inhibitors and maintenance

Antonio Gonzalez-Martin

安东尼奥·冈萨雷斯-马丁

MD, PhD

🏢Clinica Universidad de Navarra(纳瓦拉大学诊所)🌐Spain

Head, Medical Oncology Department内科肿瘤学部主任

57
h-index
2
Key Papers
2
Awards
2
Key Contributions

👥Biography 个人简介

Antonio Gonzalez-Martin is a Spanish gynecologic oncologist who served as principal investigator for the PRIMA/ENGOT-OV26 trial, one of the most practice-changing trials in ovarian cancer demonstrating niraparib maintenance benefit in all platinum-sensitive advanced ovarian cancer patients. As president of the Spanish Group for Ovarian Cancer Research (GEICO) and co-author of major ESMO/NCCN guidelines, he has shaped European ovarian cancer treatment standards. Gonzalez-Martin leads early-phase trials of novel combinations for ovarian cancer including PARP-immunotherapy combinations and antibody-drug conjugates.

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🧪Research Fields 研究领域

niraparib PRIMA trial尼拉帕尼PRIMA试验
ovarian cancer maintenance卵巢癌维持治疗
first-line ovarian cancer一线卵巢癌治疗
HRD testingHRD检测
PARP inhibitorsPARP抑制剂

🎓Key Contributions 主要贡献

PRIMA Trial Leadership

Led PRIMA/ENGOT-OV26 trial as principal investigator, establishing niraparib maintenance benefit regardless of BRCA/HRD status in first-line platinum-sensitive advanced ovarian cancer, the broadest PARP inhibitor approval in this setting.

ESMO Ovarian Cancer Guidelines

Co-authored major ESMO Clinical Practice Guidelines for ovarian cancer, defining European treatment standards incorporating PARP inhibitors, molecular testing, and surgery quality requirements.

Representative Works 代表性著作

[1]

Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer

New England Journal of Medicine (2019)

PRIMA trial establishing all-comer niraparib maintenance in first-line ovarian cancer.

[2]

ESMO Clinical Practice Guidelines for Advanced Ovarian Cancer

Annals of Oncology (2023)

European treatment standard guidelines for advanced ovarian cancer.

🏆Awards & Recognition 奖项与荣誉

🏆ESMO Award for Excellence in Gynecologic Oncology
🏆GEICO Scientific Achievement Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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