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genitourinary-oncology / genitourinary-oncologyRenal Cell Carcinoma

Sumanta Pal

苏曼塔·帕尔

MD

🏢City of Hope Comprehensive Cancer Center(希望之城综合癌症中心)🌐USA

Clinical Professor and Co-Director, Kidney Cancer Program临床教授兼肾癌项目联合主任

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Key Papers
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Key Contributions

👥Biography 个人简介

Sumanta Pal is a leading kidney cancer expert at City of Hope, known for advancing cabozantinib combinations and IO-based regimens in renal cell carcinoma. He has led multiple international trials improving outcomes for metastatic RCC patients and authored foundational treatment guidelines.

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🧪Research Fields 研究领域

GU Oncology泌尿生殖系统肿瘤学
Renal Cell Carcinoma肾细胞癌
Bladder Cancer膀胱癌
Molecular Targeted Therapy分子靶向治疗

🎓Key Contributions 主要贡献

Cabozantinib in Renal Cell Carcinoma

Led studies establishing cabozantinib as a preferred second-line therapy for metastatic RCC, demonstrating superior PFS versus everolimus in the METEOR trial analysis.

Genomic Profiling in RCC

Conducted landmark genomic studies identifying actionable mutations in metastatic RCC, connecting molecular subtypes to treatment selection and informing precision oncology approaches.

Representative Works 代表性著作

[1]

Cabozantinib versus Everolimus in Advanced Renal Cell Carcinoma

New England Journal of Medicine (2015)

METEOR trial establishing cabozantinib superiority over everolimus in previously treated metastatic RCC.

[2]

Genomic Determinants of Outcomes in Metastatic Clear Cell Renal Cell Carcinoma

European Urology (2020)

Identified genomic alterations predicting response to VEGF-targeted and immunotherapy regimens in mRCC.

🏆Awards & Recognition 奖项与荣誉

🏆American Society of Clinical Oncology Merit Award
🏆Kidney Cancer Association Young Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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