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research / researchCancer Epidemiology & Prevention

Scott Lippman

斯科特·利普曼

MD

🏢UC San Diego Moores Cancer Center(加州大学圣地亚哥分校穆尔斯癌症中心)🌐USA

Director Emeritus, Moores Cancer Center; Professor of Medicine, Division of Hematology-Oncology穆尔斯癌症中心荣誉退休主任；血液肿瘤科医学教授

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h-index
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Key Papers
4
Awards
2
Key Contributions

👥Biography 个人简介

Scott Lippman is a world authority in cancer chemoprevention who has led landmark trials of retinoids, celecoxib, and targeted agents for lung, head and neck, and aerodigestive tract cancers. His translational research bridging molecular biology and clinical prevention has defined the field of precision chemoprevention.

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🧪Research Fields 研究领域

Cancer Chemoprevention癌症化学预防
Lung Cancer Prevention肺癌预防
Head and Neck Cancer Prevention头颈癌预防
Retinoids and Celecoxib维甲酸与塞来昔布

🎓Key Contributions 主要贡献

Lung Cancer Chemoprevention

Directed pivotal trials of isotretinoin and other retinoids for secondary prevention of second primary tumors in head and neck and lung cancer survivors, establishing the concept of field cancerization prevention.

COX-2 Inhibition in Prevention

Led clinical investigations of celecoxib for oral premalignant lesions and lung cancer prevention, generating evidence on the role of arachidonic acid pathway modulation in cancer chemoprevention.

Representative Works 代表性著作

[1]

Celecoxib in the prevention of recurrent colorectal adenomas

New England Journal of Medicine (2006)

Demonstrated COX-2 inhibitor celecoxib significantly reduced adenoma recurrence, establishing a biological target for colorectal chemoprevention.

[2]

13-cis-retinoic acid and cancer prevention in head and neck cancer survivors

Journal of the National Cancer Institute (1993)

Landmark randomized trial showing isotretinoin reduced second primary tumors in head and neck cancer patients, founding modern chemoprevention trials.

🏆Awards & Recognition 奖项与荣誉

🏆AACR Joseph H. Burchenal Award for Clinical Cancer Research
🏆NCI PREVENT Cancer Program Leadership Award
🏆ASCO Cancer Prevention Award
🏆American Cancer Society Clinical Research Professorship

📄Data Sources 数据来源

Institution

Last updated: 2026-01-15 | All information from publicly available academic sources

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