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research / researchCancer Epidemiology & Prevention

Rowan Chlebowski

罗旺·赫莱博夫斯基

MD, PhD

🏢City of Hope National Medical Center(希望之城国家医疗中心)🌐USA

Medical Oncologist; Professor of Medicine; Senior Researcher, Women's Health Initiative肿瘤内科医生；医学教授；女性健康倡议高级研究员

95
h-index
2
Key Papers
4
Awards
2
Key Contributions

👥Biography 个人简介

Rowan Chlebowski is a premier authority on breast cancer prevention in postmenopausal women, with decades of leadership in the Women's Health Initiative. His research on tamoxifen, aromatase inhibitors, hormone therapy, and dietary fat has fundamentally shaped breast cancer prevention guidelines worldwide.

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🧪Research Fields 研究领域

Breast Cancer Prevention乳腺癌预防
Tamoxifen and SERMs他莫昔芬与选择性雌激素受体调节剂
Women's Health Initiative女性健康倡议
Postmenopausal Cancer Risk绝经后癌症风险

🎓Key Contributions 主要贡献

Hormone Therapy and Breast Cancer (WHI)

As a WHI principal investigator, contributed pivotal findings that combined estrogen-progestin hormone therapy significantly increased breast cancer incidence, leading to a worldwide decline in hormone therapy use.

Dietary Fat and Breast Cancer Outcomes

Led the WHI dietary modification trial demonstrating a low-fat dietary pattern reduced breast cancer mortality, providing the first randomized trial evidence for diet-based breast cancer secondary prevention.

Representative Works 代表性著作

[1]

Low-fat dietary pattern and breast cancer mortality: the WHI randomized controlled trial

JAMA Oncology (2017)

Demonstrates that a low-fat dietary pattern is associated with improved breast cancer survival, supporting dietary intervention as part of cancer prevention strategy.

[2]

Association of menopausal hormone therapy with breast cancer incidence: a WHI update

JAMA Internal Medicine (2020)

Long-term WHI follow-up confirming differential breast cancer risks with estrogen-only versus combined hormone therapy formulations.

🏆Awards & Recognition 奖项与荣誉

🏆ASCO Breast Cancer Prevention Award
🏆NCI Outstanding Investigator Award
🏆City of Hope Physician-Scientist Excellence Award
🏆American Cancer Society Research Scholar

📄Data Sources 数据来源

Institution

Last updated: 2026-01-15 | All information from publicly available academic sources

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