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Robert Langer

罗伯特·兰格

ScD

🏢Massachusetts Institute of Technology(麻省理工学院)🌐USA

David H. Koch Institute Professor, Department of Chemical Engineering大卫·科赫学院教授,化学工程系

165
h-index
2
Key Papers
5
Awards
2
Key Contributions

👥Biography 个人简介

World's most cited engineer and pioneer of controlled drug delivery. Co-invented lipid nanoparticle (LNP) technology foundational to mRNA cancer vaccines and COVID-19 vaccines. Holds over 1,400 patents; member of all four US National Academies.

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🧪Research Fields 研究领域

Nanoparticle Drug Delivery纳米粒子药物递送
Lipid Nanoparticles脂质纳米粒子
mRNA Cancer VaccinesmRNA癌症疫苗
Controlled Release Systems控释系统
Polymer Biomaterials聚合物生物材料

🎓Key Contributions 主要贡献

Lipid Nanoparticle mRNA Delivery

Co-developed LNP formulations enabling stable mRNA encapsulation and intracellular delivery, directly enabling personalized mRNA cancer vaccines and the mRNA COVID-19 vaccine platform.

Controlled-Release Cancer Therapy

Pioneered polymer-based implantable drug delivery systems, including GLIADEL wafer for glioblastoma, transforming local chemotherapy delivery and reducing systemic toxicity.

Representative Works 代表性著作

[1]

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

New England Journal of Medicine (2020)

Foundational LNP-mRNA delivery study that established the platform used for personalized cancer vaccine approaches.

[2]

Nanocarriers as an Emerging Platform for Cancer Therapy

Nature Nanotechnology (2007)

Landmark review defining nanocarrier design principles for targeted cancer drug delivery, cited thousands of times.

🏆Awards & Recognition 奖项与荣誉

🏆National Medal of Science (2006)
🏆Charles Stark Draper Prize (2002)
🏆Millennium Technology Prize (2008)
🏆Wolf Prize in Chemistry (2022)
🏆Queen Elizabeth Prize for Engineering (2015)

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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