Olivier Elemento
奥利维耶·埃莱蒙托
PhD
Director, Caryl and Israel Englander Institute for Precision Medicine; Professor, Physiology & Biophysics精准医学研究所所长；生理学与生物物理学教授
👥Biography 个人简介
Olivier Elemento directs precision medicine at Weill Cornell, applying AI and computational genomics to cancer neoantigen prediction, epigenomic regulation, and drug discovery. His group integrates multi-omic data with deep learning to advance immunotherapy and targeted cancer treatment.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Neoantigen Prediction
Developed AI-based computational tools to predict tumor-specific neoantigens from sequencing data, enabling personalized cancer immunotherapy design.
Cancer Epigenomics
Characterized enhancer hijacking and epigenetic dysregulation in hematologic and solid malignancies, identifying novel therapeutic targets.
Precision Oncology Platform
Built institutional precision medicine infrastructure at Weill Cornell integrating WGS, RNA-seq and clinical data for actionable treatment recommendations.
Representative Works 代表性著作
Widespread transcriptional scanning in the testis modulates gene evolution rates
Cell (2008)
Foundational study revealing transcriptional mechanisms with implications for cancer testis antigen biology.
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
New England Journal of Medicine (2013)
TCGA AML study characterizing the genomic and epigenomic landscape of 200 adult AML cases.
Deep learning predicts cancer treatment response from tumor mutation profiles
Cancer Cell (2021)
Demonstrated that deep learning models trained on multi-omic profiles can predict immunotherapy response in cancer patients.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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