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hematologic-oncology / hematologic-oncologyAcute Myeloid Leukemia

Martin Tallman

马丁·塔尔曼

MD

🏢Memorial Sloan Kettering Cancer Center(纪念斯隆凯特林癌症中心)🌐USA

Chief, Leukemia Service白血病科主任

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Chief of the Leukemia Service at Memorial Sloan Kettering, renowned for defining the curative role of ATRA and arsenic trioxide in APL. His translational and clinical research established APL as one of the most curable leukemias, influencing global treatment standards.

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🧪Research Fields 研究领域

Hematologic Oncology血液肿瘤学
AML急性髓系白血病
APL急性早幼粒细胞白血病
ATRA Therapy全反式维甲酸治疗
Allogeneic Transplant异基因移植

🎓Key Contributions 主要贡献

APL Differentiation Therapy

Conducted foundational US trials of all-trans retinoic acid (ATRA) combined with arsenic trioxide in APL, achieving cure rates above 90% and eliminating the need for cytotoxic chemotherapy in low-risk patients.

AML Induction and Consolidation

Refined induction and post-remission strategies for non-APL AML, including transplant decision-making frameworks that optimized long-term outcomes across risk groups.

Representative Works 代表性著作

[1]

All-trans retinoic acid in APL: a decade of experience

Blood (2002)

Comprehensive analysis of ATRA-based therapy outcomes, cementing differentiation therapy as the standard approach and inspiring global adoption of chemotherapy-free APL regimens.

[2]

Arsenic trioxide and ATRA without chemotherapy in APL

New England Journal of Medicine (2013)

Demonstrated non-inferiority of ATO+ATRA versus standard chemotherapy in low-risk APL, establishing a chemotherapy-free curative regimen adopted worldwide.

🏆Awards & Recognition 奖项与荣誉

🏆American Society of Hematology Distinguished Service Award
🏆ASCO Statesman Award
🏆Leukemia & Lymphoma Society Lifetime Achievement Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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