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Maria Jose Alonso

玛丽亚·何塞·阿隆索

PhD

🏢University of Santiago de Compostela(圣地亚哥-德孔波斯特拉大学)🌐Spain

Professor, Department of Pharmacy and Pharmaceutical Technology; Founder, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS)药学与药学技术系教授;分子医学与慢性病研究中心(CIMUS)创始人

80
h-index
2
Key Papers
5
Awards
2
Key Contributions

👥Biography 个人简介

World leader in mucosal nanoparticle drug delivery, chitosan-based nanoparticles, and non-invasive vaccine delivery platforms. Over 30 years of contributions to polymer nanoparticle formulations for mucosal cancer immunotherapy, antigen delivery, and nasal/oral drug administration. Highly cited European nanomedicine pioneer.

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🧪Research Fields 研究领域

Mucosal Nanoparticle Delivery黏膜纳米粒子递送
Chitosan Nanoparticles壳聚糖纳米粒子
Oral Cancer Vaccines口服癌症疫苗
Nasal Drug Delivery鼻腔药物递送
Proteic Nanocarriers蛋白质纳米载体

🎓Key Contributions 主要贡献

Chitosan Nanoparticles for Mucosal Vaccine Delivery

Developed chitosan and PLA/PLGA nanoparticles for mucosal antigen delivery via nasal and oral routes, demonstrating potent mucosal and systemic anti-tumor immune responses in cancer vaccine models.

Proteic Nanocarrier Platforms

Engineered albumin, zein, and gliadin protein-based nanocarriers for encapsulation and controlled release of anticancer drugs and nucleic acids across mucosal barriers.

Representative Works 代表性著作

[1]

Chitosan Nanoparticles: A New Vehicle for Nasal Delivery of Proteins

Pharmaceutical Research (1994)

Seminal demonstration of chitosan nanoparticles enabling efficient nasal mucosal protein and antigen delivery, foundational to mucosal nanomedicine field.

[2]

Nanostructured Lipid Carriers for Cancer Immunotherapy

Journal of Controlled Release (2018)

Showed lipid nanocarriers enhancing mucosal antigen uptake and dendritic cell activation for cancer vaccine applications.

🏆Awards & Recognition 奖项与荣誉

🏆Controlled Release Society Distinguished Service Award
🏆Spanish National Research Prize (Premio Nacional de Investigación)
🏆Galien Prize Spain
🏆EUFEPS Award for Pharmaceutical Sciences
🏆Real Academia de Farmacia de España Medal

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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