Maria Jose Alonso
玛丽亚·何塞·阿隆索
PhD
Professor, Department of Pharmacy and Pharmaceutical Technology; Founder, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS)药学与药学技术系教授;分子医学与慢性病研究中心(CIMUS)创始人
👥Biography 个人简介
World leader in mucosal nanoparticle drug delivery, chitosan-based nanoparticles, and non-invasive vaccine delivery platforms. Over 30 years of contributions to polymer nanoparticle formulations for mucosal cancer immunotherapy, antigen delivery, and nasal/oral drug administration. Highly cited European nanomedicine pioneer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Chitosan Nanoparticles for Mucosal Vaccine Delivery
Developed chitosan and PLA/PLGA nanoparticles for mucosal antigen delivery via nasal and oral routes, demonstrating potent mucosal and systemic anti-tumor immune responses in cancer vaccine models.
Proteic Nanocarrier Platforms
Engineered albumin, zein, and gliadin protein-based nanocarriers for encapsulation and controlled release of anticancer drugs and nucleic acids across mucosal barriers.
Representative Works 代表性著作
Chitosan Nanoparticles: A New Vehicle for Nasal Delivery of Proteins
Pharmaceutical Research (1994)
Seminal demonstration of chitosan nanoparticles enabling efficient nasal mucosal protein and antigen delivery, foundational to mucosal nanomedicine field.
Nanostructured Lipid Carriers for Cancer Immunotherapy
Journal of Controlled Release (2018)
Showed lipid nanocarriers enhancing mucosal antigen uptake and dendritic cell activation for cancer vaccine applications.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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