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gi-oncology / gi-oncologyPancreatic Cancer

Margaret Tempero

玛格丽特·坦佩罗

MD

🏢University of California, San Francisco(加利福尼亚大学旧金山分校)🌐USA

Distinguished Professor of Medicine; Director, Pancreas Center医学杰出教授;胰腺中心主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Margaret Tempero is one of the foremost authorities on pancreatic cancer treatment, having led landmark clinical trials of nab-paclitaxel plus gemcitabine and co-chaired NCCN guidelines that shape global standards of care for PDAC.

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🧪Research Fields 研究领域

Pancreatic Cancer胰腺癌
GI Oncology消化道肿瘤学
Clinical Trials临床试验
Nab-Paclitaxel白蛋白结合型紫杉醇

🎓Key Contributions 主要贡献

Nab-Paclitaxel Clinical Trials

Co-led the MPACT trial establishing nab-paclitaxel plus gemcitabine as a standard first-line regimen for metastatic pancreatic cancer, leading to FDA approval and widespread adoption.

NCCN Guidelines Leadership

Served as chair of NCCN Pancreatic Adenocarcinoma Guidelines Panel for many years, shaping evidence-based treatment recommendations used by oncologists worldwide.

Pancreatic Cancer Research Advocacy

Founded and directed the UCSF Pancreas Center and led the Pancreatic Cancer Action Network scientific advisory efforts, accelerating translational research and clinical development.

Representative Works 代表性著作

[1]

Nab-paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial

Journal of the National Cancer Institute (2015)

Long-term follow-up from MPACT confirming survival benefit of nab-paclitaxel/gemcitabine combination in metastatic PDAC.

[2]

NCCN Clinical Practice Guidelines in Oncology: Pancreatic Adenocarcinoma

Journal of the National Comprehensive Cancer Network (2023)

Comprehensive evidence-based guidelines for PDAC management, updated annually and adopted globally as the standard reference.

🏆Awards & Recognition 奖项与荣誉

🏆Pancreatic Cancer Action Network Lustgarten Award for Scientific Excellence
🏆ASCO Special Recognition Award for Pancreatic Cancer Research
🏆American Gastroenterological Association Distinguished Achievement Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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