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genitourinary-oncology / genitourinary-oncologyTesticular Cancer

Lawrence Einhorn

劳伦斯·爱因霍恩

MD

🏢Indiana University Melvin and Bren Simon Comprehensive Cancer Center(印第安纳大学梅尔文与布伦·西蒙综合癌症中心)🌐USA

Distinguished Professor of Medicine, Lance Armstrong Foundation Professor医学杰出教授、兰斯·阿姆斯特朗基金会讲席教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Lawrence Einhorn is the pioneer who developed BEP chemotherapy (bleomycin, etoposide, cisplatin), transforming testicular cancer from a fatal disease to one with over 95% cure rates. His landmark 1977 study is among the most consequential in oncology history, saving hundreds of thousands of lives.

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🧪Research Fields 研究领域

GU Oncology泌尿生殖系统肿瘤学
Testicular Cancer睾丸癌
BEP ChemotherapyBEP化疗方案
Germ Cell Tumors生殖细胞肿瘤

🎓Key Contributions 主要贡献

BEP Chemotherapy Regimen

Developed and validated the BEP (bleomycin, etoposide, cisplatin) chemotherapy regimen in 1977, achieving cure rates above 95% in disseminated testicular cancer and establishing a paradigm for curative chemotherapy.

Salvage Therapy in Testicular Cancer

Pioneered high-dose chemotherapy with autologous stem cell rescue as salvage therapy for relapsed germ cell tumors, providing curative options for patients failing first-line treatment.

Representative Works 代表性著作

[1]

Combination Chemotherapy in Disseminated Testicular Cancer

Annals of Internal Medicine (1977)

Landmark study establishing cisplatin-based BEP regimen achieving unprecedented cure rates in metastatic testicular cancer.

[2]

High-Dose Chemotherapy and Stem-Cell Rescue for Metastatic Germ Cell Tumors

New England Journal of Medicine (2007)

Established high-dose salvage chemotherapy as curative option for platinum-refractory testicular cancer.

🏆Awards & Recognition 奖项与荣誉

🏆ASCO David A. Karnofsky Memorial Award
🏆American Cancer Society Medal of Honor
🏆Indiana University Distinguished Alumni Award
🏆National Cancer Institute Outstanding Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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