Juan Valle
胡安·巴列
MD, FRCP, MSc
Professor of Medical Oncology; Consultant Medical Oncologist肿瘤内科学教授；肿瘤内科顾问医师
👥Biography 个人简介
Juan Valle is a leading UK oncologist internationally recognized for defining the standard of care in biliary tract cancers and advancing combination chemotherapy and targeted therapy trials in pancreatic and hepatobiliary cancers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Biliary Tract Cancer Standard of Care
Led the ABC-02 trial establishing cisplatin plus gemcitabine as the global first-line standard of care for advanced biliary tract cancers including cholangiocarcinoma and gallbladder cancer.
FGFR-Targeted Therapy Trials
Contributed to development and clinical testing of FGFR inhibitors in biliary tract and pancreatic cancers, expanding the landscape of targeted therapy options for these GI malignancies.
Pancreatic Cancer Clinical Trials
Conducted multiple phase I-III trials in advanced pancreatic cancer evaluating novel combinations and targeted agents through the Christie Cancer Research UK Centre.
Representative Works 代表性著作
Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer
New England Journal of Medicine (2010)
ABC-02 trial establishing cisplatin-gemcitabine as standard of care for advanced biliary tract cancers, a landmark global contribution.
IDH1 inhibitor ivosidenib in advanced cholangiocarcinoma with IDH1 mutation
The Lancet Oncology (2021)
ClarIDHy trial demonstrating ivosidenib improves PFS in IDH1-mutated cholangiocarcinoma, establishing a new targeted therapy standard.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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留下邮箱，当我们发布与 Juan Valle（University of Manchester / The Christie NHS Foundation Trust）相关的新研究或访谈时，我们会通知你。
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