John Marshall
约翰·马歇尔
MD
Chief of Hematology/Oncology; Director of GI Oncology血液/肿瘤科主任；消化系统肿瘤项目主任
👥Biography 个人简介
Dr. John Marshall is a pioneering GI oncologist and educator at Georgetown University. He has championed KRAS-targeted therapies in colorectal cancer and established one of the country's most productive GI oncology clinical research programs, leading major national cooperative group studies.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
KRAS-Targeted Therapy in Colorectal Cancer
Contributed to foundational trials establishing KRAS mutation status as a predictive biomarker and evaluating direct KRAS G12C inhibitors in colorectal cancer.
GI Oncology Education and Research Infrastructure
Built a national GI oncology research network and led patient advocacy initiatives that accelerated clinical trial enrollment in underserved populations.
Representative Works 代表性著作
Sotorasib for lung and colorectal cancers with KRAS G12C mutation
New England Journal of Medicine (2023)
Contributed to the CodeBreaK 200 trial demonstrating sotorasib activity in KRAS G12C colorectal cancer.
Maintenance therapy with bevacizumab or erlotinib after chemotherapy for colorectal cancer
Lancet Oncology (2019)
Led the CAIRO3 extension analysis defining optimal maintenance strategies in metastatic colorectal cancer.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Johanna Bendell
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