Maximilian Diehn

Maximilian Diehn is an Associate Professor of Radiation Oncology at Stanford University and co-director of the Stanford Cancer Institute. His laboratory develops and applies ultra-sensitive ctDNA detection methods for cancer early detection, minimal residual disease monitoring, and radiation treatment response assessment. Diehn co-developed CAPP-Seq (Cancer Personalized Profiling by deep Sequencing) — one of the most sensitive ctDNA detection methods available, capable of detecting tumor DNA at a fraction as low as one part in 100,000. CAPP-Seq has been applied to lung cancer, lymphoma, and other cancers for minimal residual disease monitoring. He has demonstrated that ctDNA levels during radiation therapy predict treatment outcome in non-small cell lung cancer, enabling real-time adaptive treatment decisions. His work bridges liquid biopsy technology with radiation oncology clinical practice.

Maximilian Diehn 是斯坦福大学放射肿瘤学副教授，也是斯坦福癌症研究所的联合主任。他的实验室开发并应用超灵敏ctDNA检测方法，用于癌症早期检测、微小残留病灶监测和放射治疗反应评估。 Diehn共同开发了CAPP-Seq（通过深度测序进行的癌症个性化分析）——目前最灵敏的ctDNA检测方法之一，能够以低至十万分之一的比例检测肿瘤DNA。