Young Lyun Oh
吴永连
MD, PhD
Professor of Pathology病理学教授
👥Biography 个人简介
Young Lyun Oh is a thyroid cancer pathologist who has made contributions to molecular pathology of thyroid carcinoma in the context of the Korean thyroid cancer epidemic, where a dramatic increase in papillary microcarcinoma diagnosis raised international debates about overdiagnosis. Her work on TERT promoter mutations in differentiated thyroid cancer contributed to understanding how these mutations predict aggressive behavior and recurrence, providing molecular support for identifying low-risk tumors appropriate for active surveillance. Oh has participated in WHO thyroid tumor classification revision and contributed to Korean national guidelines for thyroid cancer pathology reporting.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
TERT Mutations in DTC Prognosis
Contributed pathological evidence linking TERT promoter mutations to aggressive behavior in differentiated thyroid cancer, demonstrating their utility as risk stratification biomarkers for identifying patients requiring intensive treatment.
Korean Thyroid Cancer Pathology Standards
Contributed to Korean national thyroid cancer pathology reporting standards and WHO thyroid tumor classification, addressing the challenge of appropriate reporting in a setting with high screening-detected microcarcinoma prevalence.
Representative Works 代表性著作
TERT Promoter Mutations in Thyroid Cancer: Its Role as a Prognostic Indicator
European Journal of Cancer (2017)
Korean cohort study of TERT promoter mutation prognostic significance.
Molecular Characteristics of Thyroid Cancers in Koreans
Journal of Pathology (2016)
Molecular profiling of Korean thyroid cancers.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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