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Young Lyun Oh

吴永连

MD, PhD

🏢Samsung Medical Center, Sungkyunkwan University(成均馆大学三星医学中心)🌐South Korea

Professor of Pathology病理学教授

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Young Lyun Oh is a thyroid cancer pathologist who has made contributions to molecular pathology of thyroid carcinoma in the context of the Korean thyroid cancer epidemic, where a dramatic increase in papillary microcarcinoma diagnosis raised international debates about overdiagnosis. Her work on TERT promoter mutations in differentiated thyroid cancer contributed to understanding how these mutations predict aggressive behavior and recurrence, providing molecular support for identifying low-risk tumors appropriate for active surveillance. Oh has participated in WHO thyroid tumor classification revision and contributed to Korean national guidelines for thyroid cancer pathology reporting.

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🧪Research Fields 研究领域

thyroid cancer pathology甲状腺癌病理学
Korean thyroid cancer epidemiology韩国甲状腺癌流行病学
TERT promoter mutationsTERT启动子突变
well-differentiated thyroid carcinoma分化良好的甲状腺癌
follicular cell-derived carcinoma滤泡细胞来源癌

🎓Key Contributions 主要贡献

TERT Mutations in DTC Prognosis

Contributed pathological evidence linking TERT promoter mutations to aggressive behavior in differentiated thyroid cancer, demonstrating their utility as risk stratification biomarkers for identifying patients requiring intensive treatment.

Korean Thyroid Cancer Pathology Standards

Contributed to Korean national thyroid cancer pathology reporting standards and WHO thyroid tumor classification, addressing the challenge of appropriate reporting in a setting with high screening-detected microcarcinoma prevalence.

Representative Works 代表性著作

[1]

TERT Promoter Mutations in Thyroid Cancer: Its Role as a Prognostic Indicator

European Journal of Cancer (2017)

Korean cohort study of TERT promoter mutation prognostic significance.

[2]

Molecular Characteristics of Thyroid Cancers in Koreans

Journal of Pathology (2016)

Molecular profiling of Korean thyroid cancers.

🏆Awards & Recognition 奖项与荣誉

🏆Korean Society of Pathologists Research Award
🏆Korean Thyroid Association Scientific Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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