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genitourinary-oncology / genitourinary-oncologyBladder Cancer

Guru Sonpavde

古鲁·桑帕夫德

MD

🏢Dana-Farber Cancer Institute, Harvard Medical School(丹娜-法伯癌症研究所/哈佛医学院)🌐USA

Director, Bladder Cancer Program膀胱癌项目主任

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Key Papers
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Key Contributions

👥Biography 个人简介

Guru Sonpavde directs the bladder cancer program at Dana-Farber, known for pioneering studies on FGFR-targeted therapies, erdafitinib, and novel agents in urothelial carcinoma. He has led multiple clinical trials and meta-analyses establishing evidence-based treatment standards globally.

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🧪Research Fields 研究领域

GU Oncology泌尿生殖系统肿瘤学
Bladder Cancer膀胱癌
Novel Therapeutics新型治疗药物
Fibroblast Growth Factor成纤维细胞生长因子

🎓Key Contributions 主要贡献

FGFR-Targeted Therapy in Bladder Cancer

Contributed to clinical development of erdafitinib and other FGFR inhibitors in FGFR-altered urothelial carcinoma, establishing targeted therapy as a key approach in molecularly selected bladder cancer patients.

Systemic Therapy Meta-analyses

Conducted comprehensive meta-analyses of chemotherapy and immunotherapy regimens in urothelial carcinoma, providing high-level evidence to inform treatment guidelines and clinical practice recommendations.

Representative Works 代表性著作

[1]

Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma

New England Journal of Medicine (2019)

Phase II trial leading to first FDA-approved targeted therapy for FGFR-altered metastatic urothelial carcinoma.

[2]

Immune Checkpoint Inhibitors for Advanced Urothelial Carcinoma: A Systematic Review and Meta-Analysis

European Urology (2020)

Comprehensive meta-analysis defining efficacy and safety benchmarks for checkpoint inhibitors in urothelial carcinoma.

🏆Awards & Recognition 奖项与荣誉

🏆ASCO Genitourinary Cancers Symposium Merit Award
🏆Dana-Farber Distinguished Scholar Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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