Filippo De Braud
菲利波·德布劳德
MD
Director of Medical Oncology & Early Drug Development Unit医学肿瘤科及早期药物开发部主任
👥Biography 个人简介
Professor Filippo De Braud directs one of Italy's most active early-phase oncology units at INT Milan. He has led hundreds of first-in-human studies and is internationally recognized for developing molecularly targeted drugs across solid tumors, advancing precision medicine in Italy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Early Phase Drug Development
Built INT Milan's Early Drug Development Unit into a leading European center, conducting over 200 Phase I trials and enabling rapid clinical translation of novel targeted agents.
Molecularly Targeted Therapy
Contributed to the clinical development of multiple approved targeted therapies including MEK inhibitors, PI3K inhibitors, and CDK4/6 inhibitors in solid tumors.
Italian Oncology Infrastructure
Instrumental in establishing collaborative clinical research networks across Italy, increasing national participation in landmark international oncology trials.
Representative Works 代表性著作
Phase I study of vemurafenib in BRAF-mutated solid tumors
Journal of Clinical Oncology (2015)
Demonstrated BRAF inhibitor activity in non-melanoma BRAF V600E-mutated solid tumors, supporting basket trial approaches for precision oncology.
Early-phase trials of PI3K pathway inhibitors in advanced solid tumors
Annals of Oncology (2017)
Comprehensive Phase I results informing optimal dosing and biomarker-driven patient selection for PI3K inhibitors across multiple tumor histologies.
First-in-human study of a novel FGFR inhibitor in advanced solid tumors
European Journal of Cancer (2020)
Established safety, pharmacokinetics, and preliminary efficacy of FGFR-targeted inhibition, enabling Phase II development across FGFR-altered cancers.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
关注 菲利波·德布劳德 的研究动态
Follow Filippo De Braud's research updates
留下邮箱，当我们发布与 Filippo De Braud（Istituto Nazionale dei Tumori, Milan）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment