Eric Collisson
埃里克·科利森
MD
Associate Professor of Medicine; Member, UCSF Helen Diller Family Comprehensive Cancer Center医学系副教授；UCSF Helen Diller家庭综合癌症中心成员
👥Biography 个人简介
Eric Collisson defined the molecular subtypes of pancreatic cancer, establishing the classical, quasi-mesenchymal, and exocrine-like PDAC classification that underpins precision oncology approaches to this disease.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Molecular Subtyping of PDAC
Identified three transcriptomic subtypes of pancreatic cancer—classical, quasi-mesenchymal, and exocrine-like—each with distinct biological properties and differential chemotherapy sensitivity.
Precision Oncology Frameworks
Developed computational and genomic frameworks to match PDAC patients to targeted therapies based on molecular subtype and actionable alterations, advancing individualized treatment strategies.
Genomic Landscape of PDAC
Contributed to comprehensive genomic characterization of pancreatic cancer through TCGA and related consortia, identifying co-occurring mutations and pathways driving PDAC biology.
Representative Works 代表性著作
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
Nature Medicine (2011)
Seminal study defining three PDAC molecular subtypes with distinct prognoses and differential sensitivity to erlotinib and gemcitabine.
Comprehensive molecular profiling of pancreatic ductal adenocarcinoma
Cancer Cell (2017)
Integrated genomic, epigenomic, and transcriptomic analysis refining PDAC subtypes and identifying therapeutic vulnerabilities.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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