Elaine R. Mardis

Elaine Mardis is Co-Executive Director of the Institute for Genomic Medicine at Nationwide Children's Hospital and Research Institute and Professor at the Ohio State University College of Medicine. She is one of the founders of the next-generation sequencing (NGS) field. Mardis co-directed the first complete cancer genome sequence (AML patient, 2008) — the landmark paper that launched the cancer genomics era by demonstrating that whole-genome sequencing of a tumor could identify actionable somatic mutations. She oversaw sequencing of over 100 cancer genomes in the early years at Washington University. She led the Genome Institute at Washington University (WashU) for two decades, where her team played central roles in The Cancer Genome Atlas (TCGA), the Pan-Cancer Analysis of Whole Genomes (PCAWG), and developing clinical cancer genome sequencing pipelines.

Elaine Mardis 是全国儿童医院和研究所基因组医学研究所的联合执行主任，也是俄亥俄州立大学医学院教授。她是下一代测序（NGS）领域的创始人之一。 Mardis 共同指导了第一个完整的癌症基因组测序（2008年AML患者）——这篇里程碑式的论文通过证明肿瘤全基因组测序可以识别可操作的体细胞突变，开创了癌症基因组学时代。