Camilla Jandus

Camilla Jandus is an immunologist who studies how tumors evade immune recognition through modification of cell surface glycan patterns and neoantigen editing. Her laboratory discovered that cancer cells upregulate sialoglycans (Siglec ligands) that engage inhibitory Siglec receptors on NK cells and T cells, suppressing anti-tumor activity. This sialoglycan immune escape mechanism is broadly upregulated across cancer types and represents a targetable immune checkpoint. Jandus has developed anti-sialoglycan antibodies and Siglec-blocking approaches as immune escape reversal strategies and investigates neoantigen-specific T cell responses in human cancer immunotherapy.