Barnett Kramer
巴内特·克雷默
MD, MPH
Former Director, Division of Cancer Prevention, NCI; Senior Investigator美国国家癌症研究所癌症预防部原主任；高级研究员
👥Biography 个人简介
Barnett Kramer led NCI's Division of Cancer Prevention and is a foremost authority on cancer screening science, including the critical issue of overdiagnosis. His work on the National Lung Screening Trial and rigorous screening evidence evaluation has shaped international cancer screening policy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
NLST and Lung Cancer Screening
Provided NCI Division leadership overseeing the National Lung Screening Trial, which established low-dose CT screening as effective in reducing lung cancer mortality by 20%, leading to widespread clinical adoption.
Overdiagnosis Research
Championed rigorous assessment of overdiagnosis in breast, prostate, and thyroid cancer screening, providing the conceptual and empirical framework for evaluating screening harms alongside benefits.
Representative Works 代表性著作
Reduced lung-cancer mortality with low-dose computed tomographic screening (NLST)
New England Journal of Medicine (2011)
NLST primary report demonstrating 20% reduction in lung cancer mortality with low-dose CT, transforming lung cancer screening guidelines in the United States.
Overdiagnosis and overtreatment in cancer: a call to action
Journal of the National Cancer Institute (2013)
Influential perspective defining overdiagnosis across multiple cancer types and calling for research and policy reforms to balance screening benefits and harms.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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