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Andrew Tsourkas

安德鲁·祖卡斯

PhD

🏢University of Pennsylvania(宾夕法尼亚大学)🌐USA

Professor, Department of Bioengineering生物工程系教授

60
h-index
2
Key Papers
4
Awards
2
Key Contributions

👥Biography 个人简介

Expert in targeted magnetic nanoprobes for cancer imaging and theranostics. Develops iron oxide and gadolinium nanoparticles conjugated to cancer-specific antibodies and peptides for ultrasensitive MRI detection of tumors and image-guided therapy. Known for dual-mode imaging-therapy nanoparticles.

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🧪Research Fields 研究领域

Targeted MRI Nanoprobes靶向MRI纳米探针
Cancer Imaging癌症成像
Iron Oxide Nanoparticles氧化铁纳米粒子
Theranostics诊疗一体化
Antibody-Nanoparticle Conjugates抗体-纳米粒子偶联物

🎓Key Contributions 主要贡献

Targeted MRI Nanoparticles for Cancer Detection

Engineered antibody-conjugated superparamagnetic iron oxide nanoparticles (SPIONs) for tumor-specific MRI contrast enhancement, enabling sub-millimeter tumor detection in mouse models of breast and ovarian cancer.

Theranostic Nanoparticle Platforms

Developed dual-function nanoparticles combining MRI contrast with drug payload, enabling simultaneous real-time imaging of tumor drug distribution and therapeutic efficacy monitoring.

Representative Works 代表性著作

[1]

Dual-Functional Iron Oxide Nanoparticles for Detection and Treatment of Cancer

Small (2014)

Demonstrated theranostic SPIONs enabling simultaneous MRI imaging and targeted doxorubicin delivery in breast cancer xenografts.

[2]

Antisense Molecular Beacons for Imaging mRNA in Living Cells

Nature Biotechnology (2003)

Foundational work on molecular beacon nanostructures for intracellular RNA imaging, underpinning nanodiagnostic probe design.

🏆Awards & Recognition 奖项与荣誉

🏆Wallace H. Coulter Foundation Early Career Award
🏆NSF CAREER Award
🏆American Cancer Society Research Scholar Grant
🏆Penn Bioengineering Distinguished Teaching Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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